Important[]
Some items have yet to be released. Once they release they'll be added and marked with a red font.
Tier 1: Get (if the item fits your build)[]
Prime Chaos Orb (UR) - At the moment, the cream of the crop, this item is absurdly strong, allowing you to stack damage at the cost of your battle menu options, locking one for each click, until your run out of menu options, or miscs get locked out. This effect lasts for 1 turn.
Blazing / Quenching / Terra Bloodzerker (Rare) - Bloodblades, dealing +20% damage at the cost of 52 HP at the top level, with additional up to +10% damage while in the same element Bloodzerker armor. Spells get half the boost (to a maximum of +15% damage). Mage spellcasters would prefer the Bloodmage bloodblades listed below for their synergy with Bloodmage armors.
Lumenomancer Bloodblade (Rare) - The other Bloodmage bloodblades overlap with spellboosters, and therefore if you prefer casting spells as a Mage, this is the only must have. Function the same as the Bloodzerker blades above, with the bonus damage being with Bloodmage armor instead of Bloodzerker. For spellcasters, this weapon is inferior to Arcane Cutlass of Radiance if you already have it.
Regal DragonBlade (Rare) - A Melee/Magic Energy Bloodblade that deals +15%, damage, at the cost of 15% Melee in HP, unless the opponent is dragonkin, in which case pays less HP the more similar the opponent is to a dragon (You don't pay any cost against full dragons).
Steampunk Love Bow (Rare) - The only Harm 100-proc Ranged weapon.
Infinita Staff (Rare) - A Ranged/Magic weapon that sacrifices 25% of its damage and its Mastercraft towards healing 35.6% SP (Ranged form)/ 47.5% MP (Magic Form) of the damage dealt. This also applies to anything that applies effects from weapons, like weapon-based skills, and Bloodzerker/Subrace Beast Form type skills.
Tier 2: Situational[]
Maw of Chaos (UR) - A weapon that you can click on to multiply all Darkness Normal Attacks / Magic Attacks / Spells by *1.15/1.20/1.075. It isn't directly superior to Agony's Embrace due to having a special, but can be decent if you fit both into your inventory.
Hydromancer / Cryomancer (Rare) - Bloodmage bloodblades that overlap with other spell-boosters, and should be picked only if you plan on actually attacking with your weapon.
Riftwalker (Rare) - A pet that switches between increasing your Block rate, the same way boosters do (based on your Mainstat + CHA, rather than just CHA), against Fire attacks big a big amount, or dazing the opponent.
Call/Summon Shadowscythe Floater (UR) - A guest that deals *3 damage on the first turn, and spends 2 additional ones charging. This cannot be subverted, so this guest is only good if you don't mind having two guests with the same element.
Dread Fiend of Nulgath (Rare) - A darkness guest that either deals pure damage, or gives up all of its damage for a Backlash effect.
Frost Destroyer (UR) - Since there are more monsters with STR than monsters without it, it's marginally the strongest Magic weapon (barring spell-boosting items).
Fresh Asteraceae (Rare) - A weaker version of Foam Finger, but does Light damage instead.
Tier 3: Ehh[]
General of Cerberus - The Fully-Offensive version is bad, and the FD is ok, but better options exist.
General of Cerberus Shield - If your build has a lot of Burn, and for some reason you lack SP, this shield is an OK water option, but otherwise not really recommended.
Ultimate Dragon Scythe- Offering the ultimate compression between Melee/Ranged/Magic, and all the 8 elements, at the cost of being weaker than virtually anything.
Paladin Chilly (UR) - A light pet that has a damage and paralyze toggle. Depending on your preference it's in contention with the other top dogs for light. After the introduction of Happy Cloud, this was knocked down a few tiers, as Happy Cloud is a directly superior pet.
Tier 4: Waste[]
Anything else.